I have been in contact with come racing regarding their twin throttle body manifold running lean at the front and rich at the rear and this is the response from Sam Blumenstein.
This is rubbish.
The people who have had rich rear and lean front cylinders in 99% of cases are using the wrong size injectors. Injectors that are TOO large and being pulsed slowly so that there is no actual fuel spray mist but rather puddling and droplets.
The incorrect atomisation of air and fuel in circumstances like this create issues like what you describe and frankly it doesn't matter what manifold you use. Ours is more susceptible to this because it is so efficient. The runners are high and out of the heat and we require far less fuel to make big power figures.
We personally built over 500 street and race engines using our manifold since their introduction in the early 2000's and never had issues the so called experts describe.
A simple rule of thumb is to forget traditional formulas for injector size versus engine capacity and rpm when it comes to our manifold.
For example a typical 383 engine with 600 heads, 11.8:1 compression, solid roller bracket cam with 253/261 @ .050" 112 LCA and .591" net lift will make 580 BHP @ 6500 using a 24lb Bosch injector
If you do your calculations with all the online injector sizing problems there is no way this is possible, yet we did this with engines like this all day long. Plugs remained clean, consistency from cylinder to cylinder was always excellent.
The only problem with our manifold is that so called tuners and engine builders have no clue about the unique nature of it's design and they simply go ahead and apply the generic formulas to something that requires a smarter approach.
Sam